Evaluation of Lofexidine for Treatment of Opiate Withdrawal - 10

National Institutes of Health (NIH)

Status and phase: Completed; Phase 1

Conditions: Opioid-Related Disorders

Treatments: Drug: Lofexidine

Study type: Interventional

Funder types: NIH

Identifiers

NCT00000345

NIDA-3-0010-10

Y01-3-0010-10

Details and patient eligibility

About

The purpose of this study is to assess the safety of lofexidine in the treatment of opiate-dependent individuals.

Sex: All

Ages: 21 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

M/F ages 21-50. Meet DSM-IV criteria for opiate dependence. Agree to conditions of the study and sign informed consent.

Exclusion criteria

Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nuring women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical condtions that deem participation to be unsafe.