Evaluation of Macular Structural and Functional Function Following Extensive Retinal Laser Therapy in Patients With Proliferative Diabetic Retinopathy

Baqiyatallah Medical Sciences University

Status: Completed

Conditions: Diabetes Mellitus, Type 2

Treatments: Procedure: Panretinal Photocoagulation (PRP)

Study type: Interventional

Funder types: Other

Identifiers

NCT04436900

IR.BMSU.REC.1396.455

Details and patient eligibility

About

The present study is a semi-experimental clinical trial that 20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms. The variables of contrast sensitivity, macula thickness under fovea , BCVA, the width of thyroid under fovea , RNFL thickness in the four areas around the disc, and the quality of life questionnaire of all patients were recorded at the beginning of the study.Retinal and choroid under fovea thickness and RNFL thickness were assessed in four areas, one week and one month after the end of treatment, and all the variables mentioned earlier were evaluated three months after PRP surgery.

This study is single group that the outcomes are compared before and after the intervention

Enrollment: 20 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diabetes Mellitus, Type 2 with PDR
• Having conscious satisfaction

Exclusion criteria

• Patients with a history of other eye diseases
• Patients with a history of previous laser treatment
• Patients with a history of injection of Anti-VGEF
• Patients with Vitreous hemorrhage
• Patients with Macula edema
• Patients with myopia more than -3 diopters or hyperopiamore than +3 diopters

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

20 participants in 1 patient group

Intervention group

Experimental group

Description:

20 patients (40 eyes) with PDR underwent PRP with ARC with a spot number of 1,200 to 1,500 per eye and spot size 500 micron with a duration of 200 ms.

Treatment:

Procedure: Panretinal Photocoagulation (PRP)