Evaluation of Mechanisms Responsible for Coma in Patients Affected by Fulminant, Acute and Chronic Hepatic Failure

The University of Texas System (UT)

Status: Terminated

Conditions: Acute and Chronic Hepatic Failure With Developing Coma

Study type: Observational

Funder types: Other

Identifiers

NCT01582087

12-030

Details and patient eligibility

About

The purpose of this study is to understand mechanisms associated with the development of coma during hepatic failure. As of today, those mechanisms are not understood and it is difficult to intervene and prevent coma development which is often associated with mortality. Understanding the mechanism involved, may allow us to prevent coma and develop new therapies to treat this disease.

Enrollment: 11 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients (male or female), 18 years or older hospitalized or seen at UTMB clinics for chronic or acute hepatic failure will be included in the study.

Exclusion criteria

• Patients (male or female), 18 years or older hospitalized or seen at UTMB clinics that do not have a diagnosis of chronic or acute hepatic failure

Trial design

11 participants in 1 patient group

acute or chronic hepatic failure

Description:

All patients presenting at University of Texas Medical Branch (UTMB) with acute and chronic hepatic failure and who are developing coma