Evaluation of Mineralized Plasmatic Matrix With and Without Collagen Membrane in Peri-implant Bone Regeneration

Alexandria University

Status and phase: Completed; Phase 2

Conditions: Horizontal Alveolar Bone Defect; Alveolar Bone Loss

Treatments: Biological: mineralized plasmatic matrix (MPM) without collagen membrane; Biological: mineralized plasmatic matrix with collagen membrane

Study type: Interventional

Funder types: Other

Identifiers

NCT04816110

MPM & bone regeneration

Details and patient eligibility

About

This study focuses on comparing the effect of MPM with or without collagen membrane on delayed implant placement in anterior maxillary aesthetic zone.

Enrollment: 16 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with missing anterior maxillary teeth and having deficient alveolar thickness.
• Good oral hygiene
• Alveolar ridge width less than 4 mm.

Exclusion criteria

• Medically compromised patients.
• Heavy smokers.
• Current chemotherapy or radiotherapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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16 participants in 2 patient groups

mineralized plasmatic matrix with collagen membrane

Experimental group

Treatment:

Biological: mineralized plasmatic matrix with collagen membrane

mineralized plasmatic matrix without collagen membrane

Active Comparator group

Treatment:

Biological: mineralized plasmatic matrix (MPM) without collagen membrane