Evaluation of Monitoring Neuromuscular Blockade the Flexor Hallucis Compared to the Adductor Pollicis (CurHaTOF)

Poitiers University Hospital

Status: Completed

Conditions: Flexor Hallucis; Observation of Neuromuscular Block; Adductor Pollicis

Treatments: Device: Monitoring Neuromuscular Blockade adductor of the thumb.; Device: Monitoring Neuromuscular Blockade the Flexor Hallucis

Study type: Interventional

Funder types: Other

Identifiers

NCT02825121

CURHATOF

Details and patient eligibility

About

Current guidelines recommend monitoring of neuromuscular blockade at the adductor pollicis by stimulation of the ulnar nerve at the wrist.

However, in certain situations (laparoscopic surgery, cranial surgery or surgical comfort, arterial catheterization), it is impossible to access the patient's wrists, delaying monitoring, antagonizing the neuromuscular block, the emergence from anesthesia and patient extubation , leading in some cases to single injections lack of control of the reversal of the patient.

To overcome these technical difficulties, a group nerve / muscle looks interesting and often easily accessible to the anesthesiologist.

The stimulation of the posterior tibial nerve can observe a response to the flexor hallucis brevis muscle and allows quick access to monitoring the reversal before the end of the intervention.

The primary outcome was to compare the speed of recovery from neuromuscular block flexor hallux versus that of the adductor pollicis.

The secondary objective was to compare the speed of installation of deep neuromuscular block flexor hallucis versus that of the adductor pollicis.

This is a prospective, exploratory, uncontrolled, single-center for routine care.

Are included all aged patients over 18 years, ASA I or II, without guardianship, having no known allergy to Atracurium, without neuromyopathy known, emergency surgery or full stomach, predictable difficult intubation .

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• over 18 years
• Any elective surgery with single or multiple injection Atracurium for which hand and foot are accessible at the same time.
• ASA I or II patients
• free subject, without guardianship or subordination
• No opposition given by the patient after information

Exclusion criteria

• under 18 years
• known neuromyopathy
• Diabetics
• Emergency surgery and a full stomach
• predictable difficult intubation
• Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 1 patient group

Monitoring Neuromuscular Blockade

Experimental group

Description:

Monitoring Neuromuscular Blockade the Flexor Hallucis and adductor of the thumb.

Treatment:

Device: Monitoring Neuromuscular Blockade adductor of the thumb.

Device: Monitoring Neuromuscular Blockade the Flexor Hallucis