Evaluation of MRI for Prostate Cancer

Sheba Medical Center

Status: Terminated

Conditions: Prostatic Neoplasms

Treatments: Device: MRI with endo-rectal coil; Device: MR imaging with endorectal coil

Study type: Observational

Funder types: Other

Identifiers

NCT00930748

SHEBA-08-4965-OP-CTIL

Details and patient eligibility

About

The objective of this study is to evaluate imaging quality and correlation with histopathology in prostate cancer.

Full description

The objective of this study is to evaluate of the potential of endorectal 3T MRI for the staging of prostate cancer before prostatectomy or recurrence of prostate cancer after prostatectomy

Enrollment: 40 estimated patients

Sex: Male

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age of patients: up to 80 years.
• Men scheduled for radical prostatectomy due to prostate cancer or men post radical prostatectomy with suspicion of recurrence.
• Patients who are able and willing to give consent and able to have an MRI examination.

Exclusion criteria

• Contraindications to MRI including: claustrophobia, weight over 120 kg, implanted ferromagnetic materials or foreign objects, and known intolerance to the MRI contrast agent (e.g. Gadolinium or Dotarem)
• Individuals who are not able or willing to tolerate the required prolonged stationary supine position during imaging (approximately 1 hr.)
• Any rectal pathology preventing probe insertion, (as active proctitis, active ulcerative colitis, fissure ani)
• Any spinal pathology that prohibits maintaining supine position for an hour
• Patients with documented myocardial infarction within one month of protocol entry, and patients with cardiac pacemakers
• Severe cerebrovascular disease (multiple CVA or CVA within 6 months)