Evaluation of Nail Fold Microcirculation in CKD

Xuzhou Medical University

Status and phase: Unknown; Phase 4

Conditions: Chronic Renal Disease

Treatments: Drug: Alprostadil Injection; Drug: Beraprost sodium tablets

Study type: Interventional

Funder types: Other

Identifiers

NCT03682952

XYFY2018-KL034-01

Details and patient eligibility

About

To evaluation of nailfold microcirculation in patients with chronic renal failure and its intervention therapy

Full description

The aim of this study is to study the changes of Nailfold Microcirculation in patients with chronic renal failure, to clarify the correlation between the changes of Nailfold Microcirculation and renal function, and to explore whether nailfold microcirculation can be used as an indicator of renal microcirculation in patients with chronic renal failure, and to provide a noninvasive method for the clinical evaluation of renal microcirculation in patients with chronic renal failure.

Enrollment: 100 estimated patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• CKD patients
• Without dialysis
• Blood pressure ≤ 140/90mmHg

Exclusion criteria

• Polycystic kidney
• Endocrine system disease
• Cardio-cerebrovascular disease
• Rheumatic immune disease
• Peripheral vascular disease
• Hematological diseases
• Respiratory disease
• Infection

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

100 participants in 3 patient groups

Experimental group

Experimental group

Description:

Alprostadil and Beraprost sodium tablets are used to improve the microcirculation of CKD patients.

Treatment:

Drug: Beraprost sodium tablets

Drug: Alprostadil Injection

Anemia control group

No Intervention group

Description:

Anemia patients

Control group

No Intervention group

Description:

Healthy person