Evaluation of Nebulization and Positive Expiratory Pressure Combination

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status: Unknown

Conditions: Healthy Subjects; Cystic Fibrosis

Treatments: Drug: amikacine nebulization; Device: Positive expiratory pressure

Study type: Interventional

Funder types: Other

Identifiers

NCT02535130

NebuPEP

Details and patient eligibility

About

The purpose of this study is to compare the efficiency of nebulization and positive expiratory pressure combination

Enrollment: 15 estimated patients

Sex: All

Ages: 16 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Stable cystic fibrosis patients older than 16 y.o.
• Healthy subjects

Exclusion criteria

• Kidney failure
• No pregnancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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15 participants in 2 patient groups

Nebulization combined to positive expiratory pressure

Experimental group

Description:

Experimental arm

Treatment:

Device: Positive expiratory pressure

Drug: amikacine nebulization

Nebulization

Active Comparator group

Description:

Control arm

Treatment:

Drug: amikacine nebulization