Evaluation of Nutritional Status and Fatigue in Patients With Multiple Sclerosis (NUTRISEP)

Lille Catholic University

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Other: Gustatory sensitivity test using Taste strips; Procedure: Blood sampling; Other: Questionnaires

Study type: Observational

Funder types: Other

Identifiers

NCT02008669

RC-P0022

Details and patient eligibility

About

Multiple sclerosis (MS) is a chronic progressive neurological disease, the leading cause of disability after injury accidents in young adults. Among the many symptoms, fatigue is very common with a significant impact on quality of life. Also, the disability caused by multiple sclerosis can alter food intake and can cause nutritional deficiencies. Nutrients such as proteins, minerals (iron, calcium, magnesium), some vitamins (B12, 25 OHD) are often deficient in this population with consequences in physical performance such as endurance and muscle strength. We propose to study the link between fatigue and shortcomings encountered in a defined population of MS patients.

Enrollment: 360 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients between 18 and 65 years old
• Expended disability status scale (EDSS) between 0 and 7
• Diagnosis of MS according to the revised criteria of McDonald
• Clinically stable patients in the past 3 months
• Coverage of the social insurance
• Informed consent to participate

Exclusion criteria

• Cognitive disorders that can hinder answering questionnaires
• Presence of uncontrolled metabolic disease(s)
• Malabsorption
• Patients with a gastrostomy
• Active cancer under treatment
• Anorexia
• Pregnancy or breast feeding
• Severe psychiatric disorder(s)
• No informed consent to participate
• No coverage by the social insurance

Trial design

360 participants in 1 patient group

Multiple Sclerosis cases

Description:

All patients will undergo the following interventions * Gustatory sensitivity test using Taste strips * Blood sampling * Questionnaires

Treatment:

Other: Questionnaires

Other: Gustatory sensitivity test using Taste strips

Procedure: Blood sampling