Evaluation of Pacemaker Algorithms to Avoid Unnecessary Right Ventricular Pacing (ADVANTAGE)

German Heart Center Munich

Status: Completed

Conditions: Pacemaker Implantation for Sinus Node Disease

Treatments: Other: pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis function

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01803217

GER-EP-010

Details and patient eligibility

About

Unnecessary right ventricular pacing has been shown to be detrimental in recipients of implantable pacemaker or defibrillators.

The ADVANTAGE study evaluates the efficacy of two pacemaker based algorithms (atrioventricular hysteresis function versus mode switch to atrial pacing) to reduce right ventricular pacing.

Full description

Comparison of the effect of an atrioventricular hysteresis function with a mode switch to atrial pacing on the right ventricular pacing percentage in a multi-centre, prospective, randomized, single blinded, cross-over study.

Enrollment: 70 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Indication for the implantation of a dual-chamber pacemaker

Exclusion criteria

Persistent or permanent atrial tachyarrhythmias atrioventricular block 2nd or 3rd degree indication or the implantation of an defibrillator

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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70 participants in 2 patient groups

mode switch to atrial pacing

Experimental group

Treatment:

Other: pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis function

atrioventricular hysteresis function

Active Comparator group

Treatment:

Other: pacemaker programming to mode switch to atrial pacing versus atrioventricular hysteresis function