Evaluation of Paclitaxel Coated Balloon in the Treatment of Dialysis Access Dysfunction

Singapore Health Services (SingHealth)

Status: Unknown

Conditions: Kidney Failure; Dialysis Access Malfunction

Treatments: Drug: Paclitaxel Drug Coated Balloon

Study type: Observational

Funder types: Other

Identifiers

NCT04988789

2020/2320

Details and patient eligibility

About

Recent studies of paclitaxel DCB in the treatment of stenosis at dialysis vascular access have shown promising results. Paclitaxel, an anti-proliferation drug, is released during balloon inflation and potentially improve primary patency by slowing down NIH effect. However, meta-analysis have suggested that the use of paclitaxel in lower limbs have increased risk of death in patients. The effect of paclitaxel DCB on dialysis access however remains unknown. Hence, we aim to set up a database to track long-term treatment outcomes of patients treated with Paclitaxel DCB at SGH for their stenosed dialysis access

Enrollment: 500 estimated patients

Sex: All

Ages: 21 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients above 21 that is undergoing AVF/AVG fistuloplasty with paclitaxel DCB at SGH is included

Exclusion criteria

• All patients below 21