Evaluation of Pain in the Course of in Vitro Fertilization: the Endalgofiv-2 Study (ENDALGOFIV-2)

University Hospital, Lille

Status: Completed

Conditions: Infertility

Treatments: Other: Using different survey to evaluate pain

Study type: Observational

Funder types: Other

Identifiers

NCT05591521

2022_0015

2022-A01468-35 (Other Identifier)

Details and patient eligibility

About

The ENDALGOFIV study of pain assessment during the IVF pathway at Lille University Hospital, conducted from November 2018 to July 2020, showed that endometriosis patients have intense pain, particularly of a neuropathic nature, even before starting their IVF pathway compared to patients without endometriosis, but without an increase in pain scores during the IVF pathway. As a result of this study, a new pain management protocol for all patients undergoing IVF have been implemented in our MPA center. The study will be evaluated the impact of this new management.

Main objective To evaluate the effect of the change in pain management protocol in all patients (endometriotic or not) undergoing IVF treatment during the study period by comparing them to the data of the ENDALGOFIV 1 study.

Enrollment: 206 patients

Sex: Female

Ages: 18 to 43 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients who start an IVF cycle in the medically assisted procreation department of the Jeanne de Flandres Hospital (CHRU Lille)

Exclusion criteria

• Previously enrolled patient (ENDALGOFIV or ENDALGOFIV 2)
• Refusal to participate in the study
• Minor patient
• Patient over 43 years old
• BMI patient > 35
• Pregnant woman
• Unable to provide clear information to the patient
• Patient under guardianship or lack of health cover
• Patient in IVF with donation of oocyte
• IVF patients for oocyte preservation
• Patient who had already participated in the study