ClinicalTrials.Veeva

Menu

Evaluation of Patients After Cardiac Surgery: Novel Ultrasound Parameters for Quantification of Renal Perfusion & Analysis of Phenylephrines' Effect on Invasive Haemodynamics and Echocardiographic Measures

A

Aarhus University Hospital

Status and phase

Completed
Phase 4

Conditions

Renal Perfusion
Cardiac Surgery
Phenylephrine
Ultrasonography, Renal
Echocardiography
Anesthesia
Hemodynamics

Treatments

Drug: Phenylephrine
Other: Combination of PEEP and positioning

Study type

Interventional

Funder types

Other

Identifiers

NCT04419662
1-10-72-40-20
2020-000573-25 (EudraCT Number)

Details and patient eligibility

About

To investigate the influence of PEEP (Positive end-expiratory pressure), changes in preload (patient position) and changes in afterload (phenylephrine) on ultrasound measures of renal perfusion in patients after uncomplicated cardiac surgery.

To investigate the effects of phenylephrine on both invasive measures of the systemic- and pulmonary circulation and, secondarily, to assess the induced changes in echocardiographic indices of left- and right ventricular systolic- and diastolic function.

Enrollment

30 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • All patients ≥ 18 years scheduled for open elective cardiac surgery at the Department of Cardiothoracic & Vascular Surgery, Aarhus University Hospital.

Exclusion criteria

  • Insufficient ultrasonographic imaging of the kidneys
  • Known morphological kidney disease
  • Preoperative dialysis
  • Chronic atrial fibrillation
  • Planned mitral valve surgery

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

30 participants in 1 patient group

All patients included
Experimental group
Treatment:
Drug: Phenylephrine
Other: Combination of PEEP and positioning

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems