Evaluation of Patients With Lupus Nephritis Using Kidney MRI (Magnetic Resonance Imaging)

Johns Hopkins University

Status: Terminated

Conditions: SLE (Systemic Lupus)

Treatments: Device: MRI

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT06445127

IRB00354110

Details and patient eligibility

About

This study is being done to find out if a non-invasive Magnetic Resonance Imaging (MRI) examination of the kidneys may be helpful in patients with systemic lupus erythematosus (SLE).

Enrollment: 15 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male and female adults over the age of 18 who have been diagnosed with SLE and are able to undergo a kidney MRI.

Exclusion criteria

• Any patient that has undergone a renal transplant.
• Any patient that is receiving renal dialysis

Trial design

15 participants in 3 patient groups

Known Lupus Nephritis, with elevated UPCR result

Description:

Patients will have one scan at baseline, and one every 4 weeks thereafter for 3 visits. The final imaging session is after 6 months of routine therapy.

No known lupus nephritis

Description:

Patients will have one MRI

Known Lupus Nephritis, with normal Urine Protein Creatinine Ratio (UPCR) result

Description:

Patients will have one scan at baseline, and one every 4 weeks thereafter for 3 visits.