Evaluation of PD 0348292 for Preventing Blood Clots in the Lungs or Deep Leg Veins of Patients After Knee Surgery

Pfizer

Status and phase: Completed; Phase 2

Conditions: Venous Thrombosis

Treatments: Drug: Enoxaparin; Drug: PD 0348292

Study type: Interventional

Funder types: Industry

Identifiers

NCT00306254

A5571010

Details and patient eligibility

About

To study the safety and effectiveness of several doses of PD 0348292 compared to enoxaparin in preventing blood clots in the lungs or deep leg veins of patients after knee surgery

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult men or women scheduled for an elective, unilateral total knee replacement who are otherwise healthy.

Exclusion criteria

• History of deep vein thrombosis or pulmonary embolism, suspected postthrombotic state, bleeding or clotting disorders, or cardiovascular, renal or liver disease within the past year

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind