Evaluation of Periodontal Diseases and Obesity in Women

Kocaeli University

Status: Completed

Conditions: Periodontal Diseases; Obesity

Treatments: Other: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03442920

114S144

Details and patient eligibility

About

The aim of this study was to evaluate the effect of obesity and exercise on periodontal and biochemical parameters [serum, saliva and gingival crevicular fluid (GCF) adipokines (interleukin-1β, tumor necrosis factor-α, leptin, resistin and adiponectin)].

Full description

It is thought that adipokines may play a role on periodontal disease in obese subjects, periodontal disease may also aggravate the existing systemic disease by changing the inflammatory parameters in the body. The aim of this study was to evaluate the effect of obesity and exercise on periodontal and biochemical parameters [serum, saliva and gingival crevicular fluid (GCF) adipokines (interleukin-1β, tumor necrosis factor-α, leptin, resistin and adiponectin)].

Enrollment: 71 patients

Sex: Female

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Being women,
• Older than 18 yrs old,
• Not being pregnant,
• Not being disabled,
• For study group; being obese, not for healthy group being systemically health and in normal weight
• Not treated periodontological in the last 6 months

Exclusion criteria

• Younger than 18 yrs old,
• Smokers who smokes more than 10 cigarettes in a day,
• Uncontrolled systemic diseases,
• Having periodontal treatment
• who needs antibiotic prophylaxis

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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71 participants in 2 patient groups

Obese women

Experimental group

Description:

Obese women who participated exercise programme.

Treatment:

Other: Exercise

Normal weighted

No Intervention group

Description:

Normal weighted women with non-periodontitis