Evaluation of Peripartum Blood Loss and Postpartum Anaemia in Macrosomia & Gemini

G

Goethe University

Status

Enrolling

Conditions

Bloodloss in Pregnancy

Treatments

Other: Observation of Blood loss

Study type

Observational

Funder types

Other

Identifiers

NCT06201910
2023-1405

Details and patient eligibility

About

Anaemia in pregnant women occurs at a haemoglobin (Hb) concentration \<11 g/dL and treatment is essential to prevent increased maternal morbidity, fetal morbidity and mortality. Studies show a distinct risk of haemorrhage in pregnant women due to increased uterine dilatation, due to twins or macrosomic singletons. Currently, prepartum anaemia management, the influence of anaemia and the administration of foreign blood concentrates are insufficiently studied. The investigators intend to conduct a monocentric retrospective analysis of this subcohort.

Full description

Patient blood management is essentially based on three pillars, and a meta-analysis has already shown that consistent use can reduce transfusions and mortality. The WHO defines anaemia in pregnant patients as a haemoglobin (Hb) concentration <11 g/dl. Treatment of iron deficiency anaemia is essential because data show that iron deficiency anaemia is associated with increased maternal morbidity, fetal morbidity and mortality. Studies show a separate risk of bleeding in pregnant women due to increased uterine prolapse, for example in twin pregnancies or macrosomic singletons. At present, the prepartum anaemia management of patients, the influence of anaemia and the administration of foreign blood concentrates are insufficiently studied, which the investigators intend to investigate.

Enrollment

500 estimated patients

Sex

Female

Ages

18 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Pregnancy

Exclusion criteria

  • pre-existing coagulation disorder

Trial design

500 participants in 3 patient groups

Controll
Description:
Pregnant women without uterine dilation due to a twin pregnancy or a macrosomic singleton
Treatment:
Other: Observation of Blood loss
Gemini
Description:
Pregnant women with uterine dilation due to a twin pregnancy
Treatment:
Other: Observation of Blood loss
Makrosome
Description:
Pregnant women with uterine dilation due to a macrosomic singleton
Treatment:
Other: Observation of Blood loss

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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