Evaluation of Pharmacogenetic Testing In a Mental Health Population and Economic Outcomes (PGx-TIME)

Avera McKennan Hospital & University Health Center

Status: Completed

Conditions: Major Depressive Disorder 1

Treatments: Genetic: Pharmacogenetic testing

Study type: Observational

Funder types: Other

Identifiers

NCT02474680

AIHG-1420-PGxTIME

Details and patient eligibility

About

This is a non-randomized, single-case design of pharmacogenetic implementation in a mental health patient population of subjects taking antipsychotics and/or antidepressants.

Full description

This is a non-randomized, single-case design of pharmacogenetic implementation in a mental health patient population of subjects taking antipsychotics and/or antidepressants. Retrospective and prospective data will be collected on all subjects before and after pharmacogenetic recommendations have been made. Retrospective data will be collected for the previous 12 months before pharmacogenetic recommendations are made and prospective data will be collected for 12 months after pharmacogenomic recommendations have been made.

Enrollment: 84 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Must be taking either an anti-depressant or an anti-psychotic medication
• Must provide informed consent
• Must have Avera Health Plans insurance coverage
• Must have three months of participation in the Avera Care Coordination Program

Exclusion criteria

• Must not be pregnant or breastfeeding
• Must not have an active and/or unstable diagnosis of substance abuse
• Must not have a primary diagnosis of dementia, bulimia, or anorexia nervosa disorder
• Must not have had a previous pharmacogenetic evaluation

Trial design

84 participants in 1 patient group

Care Coordination Group

Description:

Patients participating in the Avera Care Coordination Program for Intervention 'Pharmacogenetic testing'

Treatment:

Genetic: Pharmacogenetic testing