Evaluation of Platelet Rich Fibrin / Biphasic Calcium Phosphate Effect Versus Autogenous Bone Graft on Reconstruction of Alveolar Cleft

Cairo University (CU)

Status: Completed

Conditions: Alveolar Ridge Abnormality

Treatments: Other: Autogenous bone graft; Other: PRF/ BCP

Study type: Interventional

Funder types: Other

Identifiers

NCT03302429

CEBD-CU-2017-09-31

Details and patient eligibility

About

P- Maxillary alveolar cleft defects I- Platelet-rich fibrin (PRF) combined with biphasic calcium phosphate (BCP) C- Autogenous bone graft O- Outcome measure : bone height, bone volume, hospital stay, operation duration T- 6 months S- Randomized controlled clinical trial this study aimed to answer a clinical question whether the use of Platelet-rich Fibrin (PRF) combined with Biphasic Calcium Phosphate (BCP), can be an alternative to autogenous bone graft in reconstruction of alveolar cleft defect in maxillary arch.

Full description

this study aimed to answer a clinical question whether the use of Platelet-rich Fibrin (PRF) combined with Biphasic Calcium Phosphate (BCP), can be an alternative to autogenous bone graft in reconstruction of alveolar cleft defect in maxillary arch

Enrollment: 18 patients

Sex: All

Ages: 8+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients suffering from maxillary alveolar cleft
• Patients' age 8 years and older

Exclusion criteria

• Syndromic cases will be excluded
• Patients suffering from platelets disorders.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

18 participants in 2 patient groups

PRF/ BCP

Experimental group

Description:

Biphasic calcium phosphate (BCP)"bioceramic bone substitute combined with platelet rich fibrin PRF

Treatment:

Other: PRF/ BCP

autogenous bone graft

Active Comparator group

Description:

Autogenous bone graft involving utilizing bone obtained from the same individual receiving the graft

Treatment:

Other: Autogenous bone graft