Evaluation of Post-ERCP Pain as a Predictor for Post-ERCP Pancreatitis (PEP-PREPARE)

Nicola Frei

Status: Unknown

Conditions: Post-ERCP Acute Pancreatitis

Treatments: Other: Visual analogue scale

Study type: Observational

Funder types: Other

Identifiers

NCT04770857

CTU 19/036

Details and patient eligibility

About

Pancreatitis is the most common complication after ERCP, although its frequency varies significantly depending on the study from < 2% up to 40%.

Based upon data from studies that have included unselected patients, post-ercp pancreatitis (PEP) is mild, moderate, and severe in 45%, 44%, and 11% of cases, respectively. Dysfunction of the sphincter Oddi, female gender, younger age, previous history of pancreatitis, prolonged procedure time and pancreatic guidewire passages are well-known independent risk factors for PEP.

This study will assess whether the development of PEP can be predicted by Visual analogue scale (VAS) level 1 hour after ERCP.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >18 years
• Scheduled for ERCP for any reason

Exclusion criteria

• Absence of consent
• Language barrier
• No endoscopic advance to the papilla vateri
• Active pancreatitis at the time of the procedure
• Mental disability