Evaluation of Potential Vitamin D Effects on Muscle: a Pilot Study

University of Wisconsin (UW)

Status: Completed

Conditions: Dysphagia; Fecal Incontinence; Urinary Incontinence

Treatments: Other: Ergocalciferol (vitamin D2)

Study type: Interventional

Funder types: Other

Identifiers

NCT00593996

2005-1224

Details and patient eligibility

About

People who do not have adequate amounts of vitamin D develop weakness of leg and arm muscles. This study will determine if vitamin D supplementation benefits muscle functions important for swallowing, bladder and bowel function.

Enrollment: 50 estimated patients

Sex: All

Ages: 70+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who present for evaluation to the UW Geriatric clinic including Dr. Pryzbelski's subspecialty, or Osteoporosis clinics
• Age 70 years or older
• Cognitively intact, as determined by the attending physicians at above mentioned clinics

Exclusion criteria

• History of, on ongoing, renal failure
• History of liver failure
• Known malabsorption
• Known disorders of parathyroid function, hyper/hypocalcemia, or other abnormalities of calcium or phosphate metabolism
• Known history of vitamin D intoxication or granulomatous disease
• active seizure disorder
• Pain associated with temporomandibular joint (TMJ)

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 1 patient group, including a placebo group

1

Placebo Comparator group

Description:

oral placebo 3 times weekly

Treatment:

Other: Ergocalciferol (vitamin D2)