Evaluation of PrEP-30: a Demonstration Project of Pre-exposure Prophylaxis for MSM and Other High-risk Group Clients at the Thai Red Cross Anonymous Clinic

Thai Red Cross AIDS Research Centre

Status: Invitation-only

Conditions: HIV Prevention

Treatments: Drug: PrEP

Study type: Observational

Funder types: Other

Identifiers

NCT02437981

PrEP-30 demonstration project

Details and patient eligibility

About

PrEP-30 is a demonstration project to assess the feasibility of providing oral PrEP to MSM and other individuals at-risk for HIV in Bangkok, Thailand as a service that is funded entirely through user fees. Tenofovir disoproxil fumarate/emtricitabine PrEP is provided part of a combined HIV prevention program that includes risk-reduction counseling, regular HIV testing, and the provision of condoms and lubricants. PrEP-30 is implemented at the Thai Red Cross AIDS Research Centre, at the site of the largest HIV counseling and testing center in Thailand.

Enrollment: 20,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

1. Age > 18 years

2. HIV test negative

3. Creatinine clearance > 60 ml/min

4. No contraindication or allergy to PrEP medications (TDF/FTC)

5. At least one risk factor for HIV infection within the previous 6 months:

   • sex partner known to be HIV positive

   • works as commercial sex worker

   • use of PEP for sexual exposure

   • injection drug use

   • any STI (syphilis, gonorrhea, chlamydia)

   • > 5 sex partners

   • inconsistent condom use with high-risk partners, including MSM, IDU

     • MSM: any insertive or receptive anal sex without condom
     • Women: any sex without condom with high-risk male partner (MSM, IDU, multiple female partners)
     • Heterosexual men: any sex without condom with high-risk female partner (commercial sex worker, IDU, multiple male partners)

Exclusion Criteria: -