ClinicalTrials.Veeva

Menu

Evaluation of Prognosis Factors of Neurological Evolution in Cardiac Arrest (ACR)

Grenoble Alpes University Hospital Center (CHU) logo

Grenoble Alpes University Hospital Center (CHU)

Status

Completed

Conditions

Cardio Respiratory Arrest

Treatments

Device: Synchronized Intermittent Mandatory Ventilation
Device: Pupillary light reflex surveillance
Other: Electroencephalography
Other: Therapeutic hypothermia
Device: Transcranial Doppler

Study type

Interventional

Funder types

Other

Identifiers

NCT02849561
38RC13.713

Details and patient eligibility

About

With the repercussion of 55 cases eachyear for 100 000 inhabitants in France, cardio respiratory arrest is a public health issue.

The goal of this study is to evaluate the pupillary light reflex measured by the dimension of the pupil (diameter) as a prognosis factor neurological evolution in post cardiac arrest. By participating to this study, the patient get the same tratments and exams than in a usual managing cares.

In addition of these events, the pupillary light reflex is studied as soon as the patient is accepted in the department, and then on the second day.

Currently, the evaluation of the neurological becoming rely on a multimodal clinical and paraclinical approach.

The study of the pupillary light reflex measured by the diameter of the pupil could be a prognosis factor of neurological evolution for patients in post cardiac arrest, so a reliable and available prognosis marker in patient care.

The goal of this study is to evaluate the pupillary light reflex (RPM), measured by the diameter of the pupil as a prognosis factor of neurological evaluation of admitted patients after a cardiac arrest.

Principal criteria of judgement is the percentage of the pupillary light reflex variation measured with Neurolight®, compared between two groups.

Enrollment

82 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Both gender
  • Entry in resuscitation after a cardiac arrest intra or extra-hospital
  • Resumption of a spontaneous cardiac activity
  • Affiliation to a social security system

Exclusion criteria

  • Refusal from patient or his family
  • Age under 18 years
  • Pregnant women
  • Previous neurological damages
  • Persons deprived of liberty by judicial or administrative decision

Trial design

82 participants in 2 patient groups

Favourable neurological evolution after cardiac arrest
Active Comparator group
Description:
MGOS 4-5
Treatment:
Device: Pupillary light reflex surveillance
Other: Therapeutic hypothermia
Device: Transcranial Doppler
Other: Electroencephalography
Device: Synchronized Intermittent Mandatory Ventilation
Unfavourable neurological evolution after cardiac arrest
Active Comparator group
Description:
MGOS 1-3
Treatment:
Device: Pupillary light reflex surveillance
Other: Therapeutic hypothermia
Device: Transcranial Doppler
Other: Electroencephalography
Device: Synchronized Intermittent Mandatory Ventilation

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems