Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves

Diskapi Teaching and Research Hospital

Status: Completed

Conditions: Knee Osteoarthritis

Treatments: Procedure: Genicular nerve chemical neurolysis; Procedure: Genicular nerve radiofrequency neurolysis

Study type: Interventional

Funder types: Other

Identifiers

NCT05340166

131/01

Details and patient eligibility

About

Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs. Selective denervation of the superior medial, superior lateral and inferior medial genicular nerves, which provide the sensory innervation of the knee joint, is an effective treatment method used to relieve pain and improve functional capacity. Radiofrequency neurolysis of genicular nerves (RFN) is accepted as an effective technique for the treatment of knee pain. However, due to higher equipment costs, longer procedure times, and procedure-related pain, alternative treatments are needed.

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Exclusion criteria

• Coagulation disorders
• Rheumatoid disorders
• Infections

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups

Radiofrequency Neurolysis

Active Comparator group

Description:

Radiofrequency Neurolysis of genicular nerves

Treatment:

Procedure: Genicular nerve radiofrequency neurolysis

Chemical Neurolysis

Experimental group

Description:

Chemical Neurolysis of genicular nerves

Treatment:

Procedure: Genicular nerve chemical neurolysis