Evaluation of Renal Angioplasty on Atherosclerotic Stenosis Since 2010 (PARAS)

Rennes University Hospital

Status: Completed

Conditions: Renal Angioplasty on Atherosclerotic Stenosis

Treatments: Procedure: Renal artery angioplasty

Study type: Observational

Funder types: Other

Identifiers

NCT03686358

35RC17_3069

Details and patient eligibility

About

The interest of renal angioplasty in the nosological framework of atherosclerotic stenosis has been significantly challenged by STAR and ASTRAL clinical trials in 2009, confirmed by the CORAL study in 2014.

These studies did not show any benefit of the gesture on renal function, morbidity and cardiovascular mortality or the tension control. The aim of the study is to evaluate renal angioplasty on atherosclerotic stenosis.

Full description

Previous studies did not concern the indication of renal angioplasty in some high-risk situations, such as malignant or resistant renal vascular hypertension, OAP (Acute pulmonary oedema) flash or acute renal failure of ischemic origin.

There is no work in the literature that has studied retrospectively the evolution of angioplasty practices renal artery disease on atherosclerotic stenosis since 2009, nor their remote results of the gesture.

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• OAP flash: hospitalization for Acute congestive heart failure without any other identified etiology than renal artery stenosis
• Resistant arterial hypertension under treatment including a diuretic
• Acute renal failure or ischemic renal failure quickly progressive
• Radiological criteria: renal ischemia visualized at arterial time of angio-CT or renal angio-MRI

Exclusion criteria

• Renal transplant patients
• Patients with another etiology of secondary hypertension, including fibro-muscular dysplasia of renal artery
• Restenosis on stent, angioplasty of accessory renal artery
• Patients subject to legal protection (safeguard of justice, guardianship) and persons deprived of liberty
• Patients objecting to participate to the study