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Evaluation of Retinal Microvascular Change That May Develop in After Open Globe Injury

A

Akdeniz University

Status

Completed

Conditions

Eye Injury Trauma

Treatments

Diagnostic Test: Comprehensive Ophthalmologic Examination

Study type

Observational

Funder types

Other

Identifiers

NCT05771467
AKDENIZ-GOZ-001

Details and patient eligibility

About

The aim of this study is to evaluate posterior segment changes in the non-traumatic eye after open globe injury.

Full description

Globe injuries can be classified as either closed- or open-globe injuries, based on the integrity of the sclera and cornea. Open-globe injury (OGI) is characterized by a full-thickness wound of the ocular wall.

As one of the most severe forms of ocular trauma, open-globe injury (OGI) causes significant vision loss. Timely and meticulous repair of these injuries can improve patient outcomes.

OGI by rupture often occurs at the weakest point of the eye wall, which may or may not be at the actual injury site. The rupture site is most commonly found in the sclera concentric to the limbus, just posterior to the insertion of the extraocular muscles.

After trauma, changes may occur in the non-trauma eye. Retinal and choroidal circulation may change as a result of adaptation mechanisms. In this study, we evaluated the vascular densities of the control group and post-traumatic non-trauma eye.

Enrollment

100 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Be over 18 years old
  • Unilateral eye injury

Exclusion criteria

  • Be under the age of 18
  • Usage of systemic drugs or topical ocular drops
  • Bilateral eye injury
  • Having systemic disease, having ocular pathology that may decrease visual acuity

Trial design

100 participants in 2 patient groups

Trauma Group
Description:
Non-trauma eye after open globe injury determine retinal microvascular changes
Treatment:
Diagnostic Test: Comprehensive Ophthalmologic Examination
Control Group
Description:
Investigation of retinal microvascular circulation in age- and sex-matched healthy volunteers
Treatment:
Diagnostic Test: Comprehensive Ophthalmologic Examination

Trial documents
2

Trial contacts and locations

2

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Data sourced from clinicaltrials.gov

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