Evaluation of Root Coverage After the Use of Coronally Advanced Flap Either With Advanced Paltelet Rich Fibrin or Subepithilial Connective Tissue Graft in Treatment of Miller Class I and II Gingival Recession.

Cairo University (CU)

Status: Unknown

Conditions: Gingival Recession

Treatments: Procedure: CAF + (A-PRF); Procedure: CAF+SCTG

Study type: Interventional

Funder types: Other

Identifiers

NCT03695549

assistant lecturer

Details and patient eligibility

About

patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate while the intervention one will have coronally advanced flap with advanced platelet rich fibrin(A-PRF).as it represent a new generation of platelet concentrate allow for better healing and root coverage results.

Null hypothesis: In patients with Miller class I and II gingival recession, there is no difference in amount of root coverage (mm) following the application of SCTG+A-PRF compared to CAF+SCTG.

Full description

• Population (P): Patients with single Miller class I, II gingival recessions.
• Intervention (I): Coronally advanced flap (CAF) plus platelet rich fibrin (A-PRF).
• Comparator (C): Coronally advanced flap (CAF) plus subepithelial connective tissue graft (SCTG).
• Primary Outcome (O): Root coverage (mm).
• Time frame: 9 months.
• Study design: Randomized controlled clinical trial.
• Patients are to be selected from the outpatient clinic of the department of Oral Medicine and Periodontology-Cairo University

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Systemically healthy patients 18 years old and older both males and females.
• Good oral hygiene after phase I therapy.
• Miller's class I or II gingival recession.
• Not using antibiotics, steroids, chemotherapy or other medications that may modify results of the surgery and healing.
• Cooperative patients able and accept to come for follow up appointments

Exclusion criteria

• Pregnant or lactating females.
• Current Smokers.
• Patients with any systemic disease that may affect the periodontal healing.
• Teeth with endodontic treatment, buccal restoration or caries.
• Patients with poor oral hygiene

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

intervention

Active Comparator group

Description:

CAF+ APRF

Treatment:

Procedure: CAF + (A-PRF)

control

Active Comparator group

Description:

CAF+SCTG

Treatment:

Procedure: CAF+SCTG