Evaluation of Root Coverage by Connective Graft and Different Root Conditioning Methods

University of Sao Paulo

Status: Completed

Conditions: Gingival Recession

Treatments: Procedure: Control; Procedure: citric acid plus tetracycline; Procedure: antimicrobial photodynamic therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03095378

BauruSchoolDentistryPDT

Details and patient eligibility

About

The aim of this study was to evaluate the effect of two root-conditioning agents used in conjunction with subepithelial connective graft technique on root coverage outcomes. One is citric acid plus tetracycline and the other is antimicrobial photodynamic therapy.

Full description

Citric acid plus tetracycline has properties of root surface decontamination, surface demineralization and exposure of collagen fibers.

Antimicrobial photodynamic therapy has been widely used in Periodontics to obtain reduction of periodontopathogenic bacteria with absence of systemic side effects and minimal bacterial resistance. Also, it has properties of root demineralization and exposure of collagen fibers. These properties may enhance root coverage in procedures of subepithelial connective graft.

Enrollment: 14 patients

Sex: All

Ages: 20 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Gingival recession - Miller's class I or II (2 to 5 mm of height) at least in one tooth
• Indication of root coverage by dentin hypersensitivity or esthetic

Exclusion criteria

• Smokers
• Pregnancy
• Systemic medication use that could impair wound healing or surgery procedure
• Systemic diseases as diabetes, uncontrolled hypertension, coagulation diseases, kidney diseases.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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14 participants in 3 patient groups

Control

Active Comparator group

Description:

Root treatment with scaling and root planing.

Treatment:

Procedure: Control

Citric acid plus tetracycline

Experimental group

Description:

Root treatment with 50% citric acid plus 10% tetracycline, pH1, passive application for 90s.

Treatment:

Procedure: citric acid plus tetracycline

Antimicrobial photodynamic therapy

Experimental group

Description:

Antimicrobial photodynamic therapy with toluidine blue O (100ug/ml - 60s pre-irradiation - pH4) and red laser (660nm, 30 milliwatts, 45 joules per square centimeter, sweeping mode, 90s)

Treatment:

Procedure: antimicrobial photodynamic therapy