Evaluation of Sensitization to Peach and/or Cypress in Potato Sensitized Patients in a Large Cohort (CYPPOT)

University Hospital Center (CHU)

Status: Unknown

Conditions: Allergic Rhinitis

Study type: Observational

Funder types: Other

Identifiers

NCT05119478

RECHMPL21_0612

Details and patient eligibility

About

The aim of the study will be to investigate the prevalence of of sensitization to peach and/or cypress in potato sensitized patients, based on the collection of medical data from patient records consulting in the Allergy Unit of the Arnaud de Villeneuve Hospital.

Some Gibberellin-regulated protein (GRP) in fruits and pollens have been identified as allergen, and peach GRP (peamaclein) has recently emerged as a relevant food allergen in cypress pollen-hypersensitive patients. Multiple fruit allergies might be related to cross-reactivity between GRPs. Peamaclein shares 82% identity with snakin-1 from potato. Thus, because of this hight homology the investigators want to determine the prevalence of cosensitization between these 3 allergens potato, peach and cypress.

Enrollment: 594 estimated patients

Sex: All

Ages: 2 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients evaluated at the Montpellier University Hospital, Allergy Unit
• children and adult with positive skin prick test to potato from february 2013 to december 2015

Exclusion criteria

• Patients under legal protection
• Patients under guardianship or under curatorship
• Patients not capable of understanding French