Evaluation of Sloan-Charts for Assessment of Disease Progress in Multiple Sclerosis

Charité University Medicine Berlin

Status: Completed

Conditions: Multiple Sclerosis

Study type: Observational

Funder types: Other

Identifiers

NCT01272596

Sloan-Study

Details and patient eligibility

About

Impairment of visual deficits, in particular contrast acuity and contrast impairment are frequent symptoms in MS. However, visual function is not appropriately covered by the standard tools for clinical assessment, namely, the EDSS and the MSFC.

The primary aim of this study is to investigate, whether in MS patients contrast acuity and sensitivity change over a period of two years.

Secondary aims are the correlation of visual contrast parameters with structural retinal changes and quality of life.

Enrollment: 100 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinically Isolated Syndrome or definite MS (relapsing-remitting or secondary progressive course)
• Written Informed Consent

Exclusion criteria

• Relapse within the last 30 Days
• Significant Cognitive Impairment
• Severely Decreased Visual Acuity
• Preexisting Severe Retinal Pathology

Trial design

100 participants in 1 patient group

Multiple Sclerosis Patients

Description:

Patients with Clinically Isolated Syndrome or definite Multiple Sclerosis (either relapsing-remitting or secondary progressive)