Evaluation of Some Biochemical Markers of Bone Turnover in Childern and Adolescents With Type 1 Diabetes

Sohag University

Status: Not yet enrolling

Conditions: Type 1 Diabetes

Treatments: Diagnostic Test: serum ostecalcin,serum sclerostin and parathroid profile

Study type: Observational

Funder types: Other

Identifiers

NCT05892848

Soh-Med-23-05-03MS

Details and patient eligibility

About

Type 1 diabetes is associated with many longterm complications as retinopathy,neuropathy and nephropathy. Recently, several studies have linked type 1 diabetes to bone fragility.Studies conducted on patients with type 1 diabetes have concluded that bone is negatively affected in type 1 diabetes with impaired bone density,increased fracture risk and impaired bone turnover markers.

Enrollment: 100 estimated patients

Sex: All

Ages: 3 to 16 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• childern and adolsecents below 16 years of age diagnsed with type 1 diabetes for at least 1 year age and sex-matched control childern and adolsecents will be included

Exclusion criteria

• childern and adolescents with congenital bone disease, those with disorders of the parathyroid gland and those with chronic kidney disease.

Trial design

100 participants in 2 patient groups

cases group

Description:

childern and adolescents with type 1 diabetes

Treatment:

Diagnostic Test: serum ostecalcin,serum sclerostin and parathroid profile

control group

Description:

age and sex matched control childern and adolsecents

Treatment:

Diagnostic Test: serum ostecalcin,serum sclerostin and parathroid profile