Evaluation of Surgical Excision of Cardiophrenic Lymph Nodes in Patients With Advanced Ovarian Cancer

Mansoura University

Status: Unknown

Conditions: Ovarian Cancer

Treatments: Procedure: cardiophrenic lymph nodes resection

Study type: Interventional

Funder types: Other

Identifiers

NCT03235648

R/17.05.162

Details and patient eligibility

About

Evaluation of surgical excision of cardiophrenic lymph nodes in patients with advanced ovarian cancer

Full description

The role of cardiophrenic lymph node assessment and excision in advanced ovarian cancer is still debatable , correlation of radiological finding with pathological findings after reaction of radiological positive lymph nodes and its impact in diseases free survival and over all survival

Enrollment: 25 estimated patients

Sex: Female

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria

• Ovarian cancer patient (FIGO stage III-IV)
• Preoperative CT showing CPLN with short axis diameter > 5mm.
• Anathestically fit patient (ASA score I or II).
• Accepted pulmonary function test.
• Patient who received neoadjuvant chemotherapy or recurrent cases may be enrolled
• Written informed consent.
• Achievement of optimal cytoreduction intra-abdominal( No residual disease more than 1 cm )

Exclusion Criteria:

• Anathestically unfit patient
• Unresectable disease
• Patient refusal
• No detected CPLN by preoperative radiology

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

cardiophrenic nodes excision in ovarian cancer

Experimental group

Description:

We are going to evaluate the comorbidites and impact of cardiophrenic lymph nodes excision in cases of advanced ovarian cancer with positive cardiophrenic lymph nodes

Treatment:

Procedure: cardiophrenic lymph nodes resection