EValuation of Systemic Atherothrombosis in Patients With ARTerial Disease of the Lower Limbs (EVART)

Institut de l'Atherothrombose

Status: Completed

Conditions: Carotid Stenosis; Abdominal Aortic Aneurysm; Peripheral Arterial Disease

Treatments: Other: patients with newly diagnosed PAD (<1year)

Study type: Observational

Funder types: Other

Identifiers

NCT01224600

DCIC 0704

Details and patient eligibility

About

The purpose of this study is to determine the prevalence and risk factors, at the time of the diagnosis of PAD, for asymptomatic carotid stenosis and abdominal aortic aneurysm.

Full description

The EVART study is a prospective epidemiological multicenter cohort study, including patients with newly diagnosed PAD (< 1 year). Initial data on medical history, caracterisation of the PAD (risk factors, main sites and severity of the atherosclerotic lesions),clinical evaluation of undetected previous CV events, standardized US duplex examination of the abdominal aorta and carotid arteries and treatment (type and duration) are collected by the physician into an electronic medical record. A phone follow up at 3 months, 1, 2 and 3 years is realised by the Centre for Clinical Research of Grenoble. Data on mortality, revascularization, treatments prescribed (type and duration), cancer onset, cardiovascular events, carotid stenosis, abdominal aortic aneurysm are collected. All these serious adverse events are documented and reviewed by an independent critical events committee.

Enrollment: 1,056 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient with newly diagnosed PAD < 1 year
• symptomatic or asymptomatic : ABI<0.9 at rest, claudicants with ABI<0.85 after treadmill test, or symptomatic patients (Edimburgh questionnaire or trophic changes) with ABI>1.30

Exclusion criteria

• history of previous coronory or cerebrovascular event
• previous investigation of the aorta and cervical arteries
• prisoners
• subjets with no affiliation to the social security system or equivalent

Trial design

1,056 participants in 1 patient group

1

Description:

patient with newly diagnosed PAD (\< 1 year)

Treatment:

Other: patients with newly diagnosed PAD (<1year)