Evaluation of T2, T3 Sympathectomy for Postmastectomy Pain Syndrome by Pulse Oximeter

National Cancer Institute, Egypt

Status: Completed

Conditions: Analgesia

Treatments: Procedure: Chemical Neurolysis; Procedure: Thermal Radiofrequency

Study type: Interventional

Funder types: Other

Identifiers

NCT04953507

AP2104-50104

Details and patient eligibility

About

The aim of the study is to compare the efficacy of T2, T3 sympathetic block using thermal radiofrequency versus chemical neurolysis in postmastectomy pain syndrome using perfusion index derived from pulse oximetry.

Full description

Postmastectomy pain is a chronic pain condition with neuropathic nature. Several drugs and methods are used for its management. This study was designed to compare the efficacy of both thermal radiofrequency and chemical neurolysis in management of postmastectomy pain through using perfusion index derived from pulse oximetry.

Enrollment: 54 patients

Sex: Female

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female patients with postmastectomy pain syndrome
• ≥ Age 18 years
• ASA II-III

Exclusion criteria

• patient refusal
• coagulation defects
• abnormal kidney or liver functions
• local infection at site of injection
• bone metastases
• severe cardiorespiratory disease

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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54 participants in 2 patient groups

Thermal Radiofrequency

Experimental group

Description:

T2, T3 block by thermal radiofrequency lesioning at 80°c for 120 seconds

Treatment:

Procedure: Thermal Radiofrequency

Chemical Neurolysis

Active Comparator group

Description:

T2, T3 block by chemical neurolysis using 1.5 ml of phenol in saline 8% at each level

Treatment:

Procedure: Chemical Neurolysis