Evaluation of the Attitude of Pre Menopausal Women With Breast Cancer Faced With the Risk of Fertility Loss Caused by Chemotherapy

Latin American Cooperative Oncology Group (LACOG)

Status: Completed

Conditions: Breast Cancer; Fertility

Study type: Observational

Funder types: Other

Identifiers

NCT02862990

LACOG 0414

Details and patient eligibility

About

To evaluate the attitude of pre menopausal women with breast cancer faced with the risk of loss of fertility caused by chemotherapy using EORTC's Fertility Questionnaire.

Full description

To characterize the attitude of pre menopausal patients with breast cancer regarding the risks of infertility based on the following variables:

• Age at diagnosis
• Number of children
• Will of having children
• Marital status
• Scholarity
• Period of time from the diagnosis
• Time of the last menstruation period
• Chemotherapy administration
• Clinical staging at the diagnosis
• Pathological evaluation
• Documentation of the cancer therapy

Enrollment: 343 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women with age ≥ 18 and ≤ 40
• Indication of (neo) adjuvant chemotherapy
• Prior chemotherapy treatment
• Patients with menstrual periods in the last 6 months
• In use of contraceptive methods
• Without breast cancer recurrence
• Capacity to read and understand the informed consent

Exclusion criteria

• Patients which received or with indication of definitive ovarian suppression (surgery and/or radiotherapy), except temporary pharmacological ovarian suppression
• Patients whom initiated chemotherapy treatment before entering the study
• Altered state of mind, dementia, or any other psychiatry problem that can interfere in the comprehension or interpretation of the informed consent.
• Previous diagnosis of infertility

Trial design

343 participants in 1 patient group

Pre menopausal women with breast cancer

Description:

Pre menopausal women with breast cancer prior treatment in face of infertility evoked by chemotherapy