Evaluation of the Correlation Between Molecular Phenotype and Radiological Signature (by PET-scanner and MRI) of Incident WHO II and III Grade Gliomas.

GCS Ramsay Santé pour l'Enseignement et la Recherche

Status: Completed

Conditions: Glioma

Treatments: Other: Retrospective analysis

Study type: Observational

Funder types: Other

Identifiers

NCT04461002

RadioGLioSign

Details and patient eligibility

About

From the medical records of a series of patients operated on for incident grade II and III glioma, the primary objective is to evaluate the correlation between the molecular profile of tumours and preoperative imaging data (by FDG and FDOPA PET-scan and multimodal MRI).

Full description

A retrospective monocentre study of medical data (clinical, histological, molecular and imaging) contained in the medical records of patients operated on for Grade II or III incident glioma.

Enrollment: 22 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subject 18 years of age or older, having been informed of the research
• Subject operated on with an incident glioma of grade II or III, histologically confirmed (WHO 2016 classification)
• Subject for which all preoperative imaging data is available (MRI, FDG and FDOPA PET-scan)
• Subject for which molecular data of the lesion are available

Exclusion criteria

• Subject having signified his opposition to the use of his medical data
• Subject under safeguard of justice, guardianship or trusteeship
• Subject with incomplete or missing part of the molecular and/or imaging data

Trial design

22 participants in 1 patient group

Cohort

Description:

Retrospective cohort

Treatment:

Other: Retrospective analysis