Evaluation of the Dose Received by the Prostate With in Vivo Dosimetry in Patients Treated With Daily IGRT Associated With IMRT Using Two Repositioning Techniques for Localized Prostate Cancer (PROSTRACK)

Centre Georges Francois Leclerc

Status: Terminated

Conditions: Prostate Cancer

Treatments: Radiation: IGRT Associated With IMRT; Other: CBCT; Other: fiducial marker (kV imaging)

Study type: Interventional

Funder types: Other

Identifiers

NCT02279693

2014-A00122-45

Details and patient eligibility

About

This study evaluates the dose received by the prostate with in vivo dosimetry when delivering image guided radiation therapy (IGRT) associated with intensity modulated radiation therapy (IMRT) for patients with localized prostate cancer using two repositioning techniques: fiduciary markers or soft tissues.

Full description

10 participants will receive a cone beam computed tomography (CBCT) repositioning, while the other 10 will receive a kV imaging of fiducial marker repositioning. The principal objective is to evaluate and compare the dose received by the prostate using two repositioning techniques.

Enrollment: 3 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• male > 18 years
• carcinoma of the prostate histologically confirmed
• OMS 0-1
• localized stage
• favorable, intermediate and unfavorable groups according to NCCN or D'Amico classification
• patients must have signed a written informed consent form
• patients must be affiliated to a Social Health Insurance.

Exclusion criteria

• metastasis
• indication for pelvic radiation
• anticoagulant therapy
• lateral or bilateral hip replacement
• patient receiving an adult protective services
• Patient unable to comply with the required medical follow-up for geographic, social or psychological reasons

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

3 participants in 2 patient groups

CBCT

Other group

Description:

cone beam computed tomography (CBCT) repositioning

Treatment:

Radiation: IGRT Associated With IMRT

Other: CBCT

fiducial markers

Other group

Description:

kV imaging of fiducial marker repositioning

Treatment:

Other: fiducial marker (kV imaging)

Radiation: IGRT Associated With IMRT