Evaluation of the Drug-drug Interaction Between Ticagrelor and Venlafaxine When Taken Together in Healthy Volunteers

AstraZeneca

Status and phase: Completed; Phase 1

Conditions: Drug Drug Interaction

Treatments: Drug: Ticagrelor; Drug: Venlaflaxin

Study type: Interventional

Funder types: Industry

Identifiers

NCT01350921

D5130C00073

Details and patient eligibility

About

Study evaluates the drug-drug interaction between Ticagrelor and Venlafaxine when taken together in healthy volunteers

Enrollment: 22 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• a weight of at least 50 kg and a body mass index between 18 to 30 kg/m2

Exclusion criteria

• History of clinically significant disease or disorder as judged by the investigator
• Any clinically significant illness, medical/surgical procedure or trauma within 4 weeks of the first administration of drug.
• History of haemophilia, von Willebrand´s disease, lupus anticoagulant or other diseases/syndromes that may alter or increase bleeding.
• History of previous or ongoing psychiatric disease