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Evaluation of the Effect of Biofiller PRP Application on Knee Osteoarthritis

N

Necmettin Erbakan University

Status

Not yet enrolling

Conditions

Femoral Cartilage Thickness
Knee Osteoarthritis
Biofiller PRP

Treatments

Other: biofiller prp

Study type

Interventional

Funder types

Other

Identifiers

NCT06946056
Büşra Demirtaş

Details and patient eligibility

About

The aim of this study is to evaluate the effects of biofiller PRP, on pain, range of motion, quality of life, and femoral cartilage thickness in patients with knee osteoarthritis.

Full description

Patients who are admitted and diagnosed with knee osteoarthritis based on anamnesis, physical examination and imaging methods are included in the study

Enrollment

60 estimated patients

Sex

All

Ages

45 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

1-45-65 years old 2-Diagnosis of knee OA according to ACR clinical and radiological diagnostic criteria 3-Kellgren Lawrence stage II or III 4-Knee pain for at least 6 months 5-Visual analog scale (VAS) score of at least 3 or more

Exclusion criteria

1 - History of surgery or traumatic injury 2-Inflammatory arthritis 3-History of cancer, bleeding diathesis and psychiatric disease 4-Those who have a disease that limits their participation in exercises (severe chronic obstructive lung disease, severe heart failure, history of cerebrovascular events) 5-Hip and ankle problems 6-Participating in another physical therapy program in the last 3 months 7-History of intra-articular injections in the last 6 months

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

60 participants in 2 patient groups

Biofiller platelet rich plasma
Active Comparator group
Description:
Ten ml of the patient's blood wasdrawn in a syringe pre-filled with 1 mLacid citrate dextrose(anticoagulant). It wascentrifuged firstat 4000 rotations per minute (RPM)for 15 min and thenat 1500 RPM for 5 min. The upper part,i.e.,platelet-poor plasma (PPP) was withdrawn in a 5 mL syringe. PRP was incubated in hot incubator at 100a °C for 5 min and then cooled in a refrigerator for 5 min.
Treatment:
Other: biofiller prp
Platelet rich plasma
Active Comparator group
Description:
Ten ml of the patient's blood wasdrawn in a syringe pre-filled with 1 mLacid citrate dextrose(anticoagulant). It wascentrifuged firstat 4000 rotations per minute (RPM)for 15 min and thenat 1500 RPM for 5 min. The upper part,i.e.,platelet-poor plasma (PPP) was withdrawn in a 5 mL syringe
Treatment:
Other: biofiller prp

Trial contacts and locations

0

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Central trial contact

BANU ORDAHAN

Data sourced from clinicaltrials.gov

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