Evaluation of the Effect of Central Sensitivity on Pain and Functional Status After Total Knee Joint Replacement Surgery

Istanbul University

Status

Not yet enrolling

Conditions

Postoperative Pain

Arthritis

Central Sensitisation

Treatments

Procedure: Total knee arthroplasty

Study type

Observational

Funder types

Other

Identifiers

NCT06553118

2024/1010

Details and patient eligibility

About

The study is a prospective observational study designed to determine the effects of central sensitization on pain and functional status of patients before and after total knee joint replacement surgery.

The aim of this study is to evaluate whether there is a difference in preoperative and postoperative pain and functional status between patients with and without central sensitization with knee osteoarthritis.

When the literature was reviewed, it was seen that central sensitization was one of the important mechanisms that caused pain in knee osteoarthritis, and it was determined that this had negative consequences in terms of postoperative pain and improvement in functional status. In this study, the effect of central sensitization on the results will be investigated by evaluating pain and functional status before and after knee total joint prosthesis in two groups of knee osteoarthritis patients, with and without central sensitization, and by comparing the groups.

Enrollment

80 estimated patients

Sex

All

Ages

60 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Diagnosis of primary knee osteoarthritis
Planning for total joint replacement surgery for the knee
Being between the ages of 60-75

Exclusion criteria

Having secondary knee osteoarthritis
Planning for knee total joint prosthesis revision
Having uncontrolled systemic disease (such as diabetes mellitus, hypertension, thyroid disease)
Having neuromuscular disease
Having a body mass index over 40