Evaluation of the Effect of Myopic Femtosecond Laser Assisted-LASIK on Anterior Chamber Flare Values and Corneal Endothelial Cells: A Prospective Before-and-After Study

Istanbul University

Status: Completed

Conditions: Anterior Chamber Inflammation; Refractive Surgery; Cornea

Treatments: Procedure: Femtosecond laser assisted LASIK

Study type: Interventional

Funder types: Other

Identifiers

NCT04899258

06.12.2019/20/1495

Details and patient eligibility

About

This study aimed to investigate whether femtosecond laser-assisted LASIK (FS-LASIK) surgery causes inflammation in the anterior chamber and to analyze its effect on endothelial cells.

Full description

Since FS-LASIK surgery is applied using both an FS laser and an excimer laser, we aimed to determine the direct and indirect effects of these applications on the corneal endothelium, the intensity of the inflammation, and the blood-aqueous barrier in the anterior chamber. To the best of our knowledge, the effects of FS-LASIK on anterior chamber inflammation have not been previously investigated. Therefore, we evaluated these effects using objective measurement methods, such as specular microscopy and laser flare photometry.

Enrollment: 30 patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• The patients who performed Femtosecond laser assisted LASIK for myopia or myopic astigmatism.
• Uncomplicated surgery

Exclusion criteria

• Complicated surgery,
• Hyperopic or hyperopic astigmatism
• Lack of follow-up measurements

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

30 participants in 1 patient group

Pre-surgery and post-surgery

Other group

Description:

femtosecond assisted LASIK

Treatment:

Procedure: Femtosecond laser assisted LASIK