Evaluation of the Effectiveness of Prophylactic LMWH by Thromboelastography

Ege University

Status: Completed

Conditions: Malignancy

Study type: Observational

Funder types: Other

Identifiers

NCT06484231

22-AKD-64

Details and patient eligibility

About

This study aims to evaluate the necessity and effectiveness of using low molecular weight heparin (LMWH) for prophylaxis in the postoperative period in patients who underwent lobectomy due to malignancy, using thromboelastography.Blood samples taken from the patients before low molecular weight heparin prophylaxis (preoperative), before prophylaxis in the postoperative period (postoperative day 1) and after the start of postoperative prophylaxis (postoperative day 3) will be examined by thromboelastography.

Full description

General characteristics of the patients such as age, gender, presence of comorbidities, smoking, type of operation and approach applied, operation duration, TEG measurements and postoperative complication development were recorded with case forms.

Enrollment: 25 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who underwent lobectomy with thoracotomy or videothoracoscopy (VATS) due to malignancy (primary or secondary lung cancer)

Exclusion criteria

• Patients with a known diagnosis of bleeding or coagulation disorders
• Patients receiving anticoagulant and antiplatelet therapy in the preoperative period
• Patients who developed perioperative bleeding and therefore underwent perioperative blood and blood product replacement