Evaluation of the Effectiveness of the Self-developed Pulmonary Lobar Ventilation Detector

China-Japan Friendship Hospital

Status: Enrolling

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Device: Self-developed pulmonary lobar ventilation detector; Device: Chartis detection system

Study type: Observational

Funder types: Other

Identifiers

NCT05799040

2022-NHLHCRF-LX-01-0202-3

Details and patient eligibility

About

The goal of observational study is to Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector in Chronic Obstructive Pulmonary Disease. The main question it aims to answer are:Evaluation of the effectiveness of the self-developed pulmonary lobar ventilation detector.

Participants will use the self-developed pulmonary lobar ventilation detector and the imported Chartis detection system to evaluate the target pulmonary lobar collateral ventilation.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with chronic obstructive pulmonary disease who meet the GOLD diagnostic criteria
• FEV1 ≤ 45% pred and FEV1/FVC<70%
• TLC>100% pred and RV>175% pred
• CAT≥18
• >50% of emphysema destruction
• Smoking prohibition>6 months
• Sign the informed consent form

Exclusion criteria

• PaCO2>8.0 kPa, or PaO2<6.0 kPa
• 6-minute walking test<160m
• Obvious chronic bronchitis, bronchiectasis or other infectious lung diseases
• Three hospitalizations due to pulmonary infection in the past 12 months before the baseline assessment
• Previous lobectomy, LVRS or lung transplantation
• LVEF<45% and or RVSP>50mmHg
• Anticoagulant therapy that cannot be stopped before surgery
• The patient has obvious immune deficiency
• Participated in other lung drug studies within 30 days before this study
• Pulmonary nodules requiring intervention
• Any disease or condition that interferes with the completion of the initial or subsequent assessment

Trial design

40 participants in 2 patient groups

Self-developed pulmonary lobar ventilation detector

Treatment:

Device: Self-developed pulmonary lobar ventilation detector

imported Chartis detection system

Treatment:

Device: Chartis detection system