Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.

Pamukkale University

Status: Completed

Conditions: Hemorrhage; Pain, Postoperative; Analgesia; Healing Wound

Treatments: Other: Aftamed oral spray; Other: Crystalin oral spray; Drug: Majezik %0.25 oral spray; Procedure: Free gingival graft harvesting

Study type: Observational

Funder types: Other

Identifiers

NCT05386667

05.03.2019/05

Details and patient eligibility

About

In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting (FGG).

Full description

In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting. The effectiveness of these 3 different commercially available agents containing flurbiprofen, hyaluronic acid, and hypochlorous acid, after use 2., 4.7. and on the 14th day, wound healing and pain perception was compared with the control group. primary observation was obtained by visual analog scale, wound healing index, bleeding of tissue, color match, and amount of painkiller used by the patient were also recorded

Enrollment: 60 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:- Patients with systematic conditions are classified as The American Society of Anesthesiologists Class I

Exclusion Criteria:

• Pregnancy, lactation, and taking contraceptive pills.
• Oversensitivity or anaphylactic reactions which contraindicate the intervention.
• Orofacial neurological symptoms.
• Infections at operation zone.
• Psychotropic medicine, sedative, or non-steroid anti-inflammatory drugs use which can alter the sense of pain.
• Pathological mental conditions (dementia, psychosis) and lack of cooperation.
• Smoking
• Excessive gag reflex
• Operations are carried out with conscious sedation.
• Patients who do not want to sign consent.

Trial design

60 participants in 4 patient groups

Control

Description:

Patients were not given anything after FGG.

Treatment:

Procedure: Free gingival graft harvesting

Flurbiprofen

Description:

Oral spray containing 0.075 g flurbiprofen administered after FGG

Treatment:

Drug: Majezik %0.25 oral spray

Procedure: Free gingival graft harvesting

Hypochlorous acid

Description:

Oral spray containing hypochlorous acid applied after FGG

Treatment:

Other: Crystalin oral spray

Procedure: Free gingival graft harvesting

Hyaluronic acid

Description:

An oral spray containing the main component of the product is hyaluronic acid (sodium salt) with a high molecular weight of 30 mg / 100 g was given to patients after FGG

Treatment:

Other: Aftamed oral spray

Procedure: Free gingival graft harvesting