Evaluation of the Effects of Osteoperforation and Piezocorticision on Canine Retraction

Université de Montréal

Status: Terminated

Conditions: Orthodontic Treatment; Canine Retraction; Osteoperforation; Piezocorticision

Treatments: Procedure: Piezocorticision; Procedure: Osteoperforation

Study type: Interventional

Funder types: Other

Identifiers

NCT03308851

Piezo and Osteoperforation

Details and patient eligibility

About

The primary objective of this research is to compare the rate of canine retraction following the osteoperforation and piezocorticision procedures in cases of first premolar extractions. The secondary objectives are to compare the second order movement of the canine (tipping), the amount of root resorption associated with the procedures, the inflammation process by measuring the inflammatory markers in the gingival crevicular fluid, the loss of posterior anchorage by measures on the cone beam computed tomography (CBCT) 3-dimensional radiograph and on the casts and to evaluate the pain level and the impact on quality of life following each procedure using the questionnaire of the visual analogue scale (VAS) of pain.

Enrollment: 17 patients

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Dental and/or skeletal Cl I and II requiring maxillary first premolar extraction.
• Young adults 16 years and older.
• Good overall health.
• Complete adult dentition.
• Cooperative.
• Acceptable hygiene.
• Absence of any periodontal disease (gingivitis, periodontitis).

Exclusion criteria

• Non-cooperative, fearful patients or patients with intellectual disability.
• Patients requiring the regular use of nonsteroidal anti-inflammatory drugs (NSAID).
• Use of antibiotics in the last 6 months.
• Previous or current use of bisphosphonates, corticosteroids or immunosuppressive drugs.
• Smokers.
• Patients suffering from uncontrolled systemic diseases (ex. diabetes type I and II).
• Presence of oral or maxillofacial malformations (ex. cleft palate) or dental pathologies (ex. ankylosis, abscess).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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17 participants in 2 patient groups

Piezocorticision and osteoperforation group

Experimental group

Description:

All participants in this arm will receive the piezocorticision and osteoperforation procedures on the upper jaw on the left and the right side.

Treatment:

Procedure: Osteoperforation

Procedure: Piezocorticision

Control

No Intervention group

Description:

The participants in this arm will receive no treatment, but will have the same monitoring as the experimental group.