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Evaluation of the Efficacy of the Individually Adjusted Therapy Scale (ATI) on the Addiction Severity (AjusT)

U

University Hospital of Bordeaux

Status

Completed

Conditions

Addictive Behavior
Substance-Related Disorders

Treatments

Procedure: Weekly assessment ajusted
Procedure: Weekly assessment

Study type

Interventional

Funder types

Other

Identifiers

NCT03606759
CHUBX 2014/43

Details and patient eligibility

About

The management of the craving is a key element in addiction treatment as the craving is linked to the probability of relapse. Several cues could induce the craving, some generic substance-induced cues or addictive behavior-related cues (e.g. gambling-related cues), and also some more subject-specific cues. The awareness of the craving intensity and its individual cues for each patient will allow the clinician to tailor a better treatment. The aim of this study is to evaluate the efficacy of a program based on an Individually Adjusted Therapy scale added to a treatment as usual for the treatment of addiction.

Full description

Addiction is one of the most prevalent psychiatric disorders in general population. In the DSM-5, substance abuse and substance dependence have been combined into a single substance use disorder and gambling disorder is now reclassified in the new substance-related and addictive disorders category. Moreover, a criterion assessing the craving has been added. The management of craving is an important focus of addiction treatment as craving is often linked to relapse. Several cues could precipitate the craving. Some of them are substance-related or gambling-related, some other are more person-specific. Recent studies have revealed that those "individual cues" are highly predictive of craving and relapse, and suggest that they are involved in addiction chronicity. The awareness of these cues and the intensity of the craving are important to tailor a better treatment adapted to the patient's need in order to prevent relapse. The aim of this study is to evaluate the efficacy of a program that includes an Individually Adjusted Therapy scale (ATI) to help the clinician to modulate the level of care regarding of the patient's risk of relapse (based on cues, intensity and frequency of the craving). The study will consist in a randomized controlled trial comparing 2 groups of participants that are seeking treatment for substance use disorder (alcohol, opiates, tobacco, cannabis, cocaine or any other substance) or behavioral addiction in an outpatient addiction clinics in France (four inclusion sites).

All the participants will be assessed with several questionnaires that evaluate the history and the severity of addiction.

Enrollment

151 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria:

  • 18 years old or older

  • Meet DSM-5 substance use disorder diagnosis for at least one substance (alcohol, tobacco, cannabis, opiates, cocaine or any other substance) use disorder or behavioral addiction (gambling, screens, video games, food addiction, sex addiction, compulsive purchases), currently not stabilized

  • Seek treatment for this a substance use disorder or behavioral addiction

  • Beginning (or re-initiating) multi-month outpatient care for this disorder in one of the inclusion centres.

  • Ability to identify a priority substance/behavior, as main object of treatment, in case of simultaneous treatment on several addictions

  • Beneficiary of the French Social Security system

  • Give an informed consent to participate

    o Exclusion criteria:

  • Severe physical or psychiatric or addictologic condition that prevents an outpatient treatment

  • Severe physical or psychiatric condition that prevents to complete the assessment

  • Addictive disorder that requires several treatment for several substance use disorder simultaneously

  • Difficulty to understand and to write French

  • Could not be reachable by phone

  • Participate to another study that prevents to participate to another research

  • Prisoner

  • Person under law protection

  • Person under legal guardianship

Trial design

Primary purpose

Supportive Care

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

151 participants in 2 patient groups

Traitment as usual adjusted on ATI information
Experimental group
Description:
Assessments with a multidisciplinary team (doctors, nurses, psychologists, psychiatrists, social workers) once a week during 3 months.
Treatment:
Procedure: Weekly assessment ajusted
Traitment as usual
Active Comparator group
Description:
Assessments with a multidisciplinary team (doctors, nurses, psychologists, psychiatrists, social workers) once a week during 3 months.
Treatment:
Procedure: Weekly assessment

Trial contacts and locations

4

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Central trial contact

Fuschia Serre; Mélina Fatseas

Data sourced from clinicaltrials.gov

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