Evaluation of the Health Effects of the Air Purifier in Preterm Infants After Discharge

Kaohsiung Medical University

Status: Enrolling

Conditions: Premature - Weight 1000g-2499g or Gestation of 28-37weeks; Premature Birth

Treatments: Device: air purifier

Study type: Interventional

Funder types: Other

Identifiers

NCT07236996

KMUHIRB-SV(I)-20210024

Details and patient eligibility

About

Participant's baby was born prematurely and had underdeveloped lungs at birth. Most premature infants require mechanical ventilation after birth, which increases the risk of lung injury and may lead to varying degrees of bronchopulmonary dysplasia (BPD). Investigators believe that introducing an air purifier into your home environment after Participant's baby is discharged could help improve their lung development.

This study aims to non-invasively measure baby's transcutaneous carbon dioxide (PtcCO₂) levels and blood oxygen saturation (SpO₂) at home, both with and without the use of an air purifier. In addition, investigators will collect data from Kaohsiung Medical University Hospital medical records regarding the number of visits, respiratory status, height, weight, head circumference, and developmental progress. Health questionnaires will also be administered to assess changes in health outcomes and provide recommendations on improving indoor air quality in Participant's home.

Enrollment: 180 estimated patients

Sex: All

Ages: Under 6 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:Children aged 0 to 6 years who were born at less than 37 weeks of gestation.

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Exclusion Criteria:Children born at more than 37 weeks of gestation.

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Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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180 participants in 1 patient group

Comparison of Air Purifier Intervention and Frequency of Medical Visits

Experimental group

Description:

Study Arm: Experimental (Air Purifier On) vs. No Intervention (Air Purifier Off）

Treatment:

Device: air purifier