Evaluation of the Impact of Pancreatectomy on Systemic Immunity (IMMUNOPANC)

Institut Paoli-Calmettes

Status: Unknown

Conditions: Pancreatectomy; Hyperglycemia; Pancreas Cancer

Treatments: Other: Blood sampling

Study type: Interventional

Funder types: Other

Identifiers

NCT03978702

IMMUNOPANC-IPC 2018-051

Details and patient eligibility

About

The study aims at establishing the profile of the immune reaction that occurs in the early surgical suites after pancreatectomy. Blood samples will be collected before surgery, (Day-1), at day0, and after surgery at Day 1, Day 3, Day 7 at 1 year after pancreatectomy. Mass cytometry, genomic and transcriptomic approaches will be used to evaluate the immune systemic modulation after surgery.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with an indication of pancreatectomy
• Signed consent form

Exclusion criteria

• Neoadjuvant treatment
• Pregnancy

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

Indication for pancreatectomy

Experimental group

Description:

Blood sampling at different time points before and after pancreatectomy

Treatment:

Other: Blood sampling