Evaluation of the Physiopathological Phenomena and the Haemodynamic and Cerebral Metabolic Effects From Semi-seated Position to Lying Position in Patients With Brain Trauma (PULSATILITY)

University Hospital Center (CHU)

Status: Unknown

Conditions: Traumatic Brain Injury

Treatments: Other: Change from semi-seated position to supine

Study type: Interventional

Funder types: Other

Identifiers

NCT02832908

9413

Details and patient eligibility

About

Brain trauma is an important burden in traumatologic intensive care. In these patients the treatment is guided by a cluster of multimodal monitoring parameters. Despite this it is difficult to assess the actual physiopathologic status of the brain. Changing the position of these patients (semi-seated to lying position) causes changes in the hémodynamics brain conditions, so in monitoring parameters . The analysis of these changes can givr us valuable clinically informations.

Full description

Severe brain trauma (CGS < 8 ) are included. PIC, PA, PVC, EKG, airway pressure, SjO2 and NIRSS are continuously monitored.

The patients are in semi seated (30°) position. Once a day they are in supine (0°) for 30 minutes. We record every parameters before and at the end of this supine period.

After time domain and frequency domain signal processing, this parameters are compared to deduct clinical relevant conclusions.

Enrollment: 90 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with a severe head trauma estimated by the Glasgow Coma Scale and by the Glasgow Outcome Scale
• age > 18

Exclusion criteria

• Other neurological pathology

Trial design

90 participants in 1 patient group

Patients + parents

Other group

Description:

Patients with severe head trauma

Treatment:

Other: Change from semi-seated position to supine