Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease

Recep Tayyip Erdogan University Training and Research Hospital

Status: Unknown

Conditions: Preeclampsia; Periodontal Disease

Treatments: Diagnostic Test: preeclampsia; Diagnostic Test: control

Study type: Observational

Funder types: Other

Identifiers

NCT03603236

40465587-28

Details and patient eligibility

About

The primary objective of the study is to assess the incidence and severity of the periodontal infection of patients with preeclampsia.

The secondary objective of the study is to analyze the relationship between preeclampsia and periodontal infection, using clinical, biochemical and microbiological methods.

Full description

Preeclampsia is identified as an important cause for mother and newborn mortality. Inspite of extensive research, the exact etiological relations have not been established.

Periodontal disease is a subclinical and persistent infection source which induces the systemic inflammatory reactions and increases the risk of preeclampsia. It is believed that the results will set light to the etiology of preeclampsia and will help to develop strategies to prevent the disease.

Enrollment: 100 estimated patients

Sex: Female

Ages: 21 to 34 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• pregnant women with preeclampsia
• 37. weeks of pregnant women with no history of preterm labor

Exclusion criteria

• Genitourinary infection,
• pregnancy or pre-pregnancy hypertension,
• HIV infection,
• diabetes mellitus,
• multiple pregnancy, preterm labor / low birth weight,
• smoker and alcohol use history,
• IVF pregnancy,
• placental, cervical and uterine anomalies,
• pregnancy with intrauterine growth retardation,
• pregnancies with congenital or chromosomal fetal anomalies,
• significant vaginal bleeding,
• infertility stories,
• drug addicts,
• poor socioeconomic level

Trial design

100 participants in 2 patient groups

preeclampsia

Description:

18-40 aged diagnosed with preeclampsia

Treatment:

Diagnostic Test: control

Diagnostic Test: preeclampsia

control

Description:

18- 40 aged healthy females over 37. weeks of pregnant with no history of preeclampsia

Treatment:

Diagnostic Test: control

Diagnostic Test: preeclampsia